Baked John Wayne Casserole with layers of biscuits, seasoned beef, and melted cheese.

How to Make Easy John Wayne Casserole in 2025

John Wayne Casserole


Introduction

John Wayne Casserole is a hearty dish that brings comfort and joy to the dinner table. It’s packed with flavor and so easy to make! You can enjoy it any night of the week, and it’s perfect for family gatherings.

Why Make This Recipe

This casserole is great for so many reasons! It’s filling, full of delicious ingredients, and perfect for busy days. You can prepare it ahead of time and serve it to your loved ones. Plus, it’s one of those recipes that makes everyone smile!

How to Make John Wayne Casserole

Ingredients:

  • 1 lb ground beef
  • 1/2 cup diced onion
  • 1/2 cup diced bell peppers (red and green)
  • 1 packet taco seasoning
  • 1/2 cup water
  • 2 cups shredded cheddar cheese
  • 1 cup sour cream
  • 1/2 cup mayonnaise
  • 1 can (10 oz) diced tomatoes with green chilies (drained)
  • 2 cups biscuit mix (like Bisquick)
  • 1/2 cup milk

Directions:

  1. Preheat your oven to 350°F (175°C). Grease a 9×13 baking dish.
  2. In a skillet, brown the ground beef with onion and bell peppers until fully cooked. Drain grease. Add taco seasoning and water, stirring until thickened.
  3. In a bowl, mix biscuit mix and milk until smooth. Spread the dough evenly in the bottom of the prepared baking dish.
  4. Layer the seasoned beef mixture over the biscuit dough. Spread diced tomatoes evenly on top.
  5. In a bowl, combine sour cream, mayonnaise, and half of the cheddar cheese. Spread the mixture over the tomatoes. Sprinkle the remaining cheddar cheese on top.
  6. Bake for 35-40 minutes, or until the biscuit layer is cooked through and the cheese is bubbly.
  7. Let cool slightly before slicing. Top with extra sour cream or fresh parsley if desired!

How to Serve John Wayne Casserole

Serve it hot right out of the oven! You can add some extra toppings like sour cream or fresh herbs for a lovely finish. It goes well with a side salad or some warm bread, too.

How to Store John Wayne Casserole

If you have leftovers, let the casserole cool down and store it in an airtight container in the fridge. It will last for about 3-4 days. You can also freeze it for up to 2 months!

Tips to Make John Wayne Casserole

  • Use lean ground beef to make it a bit healthier.
  • Feel free to add any of your favorite veggies, like corn or black beans!
  • If you want more spice, add some jalapeños or hot sauce to the beef mixture.

Variation

You can use cooked shredded chicken or turkey instead of ground beef for a different twist. For a vegetarian version, swap the meat for black beans or lentils!

FAQs

1. Can I make this casserole ahead of time?
Yes! You can prepare it the day before and bake it when you’re ready to eat.

2. Can I use a different cheese?
Absolutely! Feel free to use Monterey Jack, pepper jack, or any cheese you love.

3. What can I serve with it?
It pairs well with a fresh salad, garlic bread, or even some rice on the side.


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